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Found 7 Enz. Inhib. hit(s) with Target = 'Peptide deformylase, mitochondrial' and Ligand = 'BDBM50089194'
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity of the compound towards Peptide deformylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibitory concentration required against peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataIC50:  10nMAssay Description:Antibacterial activity of the compound against E. coli Peptide deformylase. NiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human PDF using N-formylated peptide as substrate in presence of NAD+ by formate dehydrogenase-coupled spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human mitochondrial PDFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human peptide deformylase after 1 hr by fluorescence polarization based competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank