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Found 3 Enz. Inhib. hit(s) with Target = 'Phosphatidylcholine:ceramide cholinephosphotransferase 2' and Ligand = 'BDBM50182491'
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  1.00E+3nMAssay Description:Noncompetitive inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using 5 to 50 uM C6-NBD-ceramide as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of SMS2 (unknown origin) stably expressed in mouse ZS cells using C6-NBD-ceramide as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Mus musculus)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50182491(CHEBI:69015 | Malabaricone C)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of SMS2 in MEF cells using C6-NBD-ceramide as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by HP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed