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Found 4 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM315477'
LigandPNGBDBM315477(US10172858, Table 1.1 | US10172858, Table 1.22)
Affinity DataIC50: <100nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM315477(US10172858, Table 1.1 | US10172858, Table 1.22)
Affinity DataIC50: >200nMAssay Description:Inhibition of PI3K-gamma (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM315477(US10172858, Table 1.1 | US10172858, Table 1.22)
Affinity DataIC50: <1.00E+3nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM315477(US10172858, Table 1.1 | US10172858, Table 1.22)
Affinity DataKd:  3.70nMAssay Description:Inhibition of human PI3Kgamma (144 to 1102 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed