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Found 4 Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor alpha' and Ligand = 'BDBM21079'
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM21079(1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM21079(1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-...)
Affinity DataKd:  4.20nMAssay Description:Binding constant for PDGFRA kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM21079(1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-...)
Affinity DataKd:  4.20nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM21079(1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-...)
Affinity DataKd:  4.20nMAssay Description:Binding constant for PDGFRA kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed