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Found 1 Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor alpha [D842V]' and Ligand = 'BDBM504399'
TargetPlatelet-derived growth factor receptor alpha [D842V](Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM504399((S)-1-(2-(4-(3-chloro-6-(1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50: <1nMAssay Description:KIT, KIT mutant, and PDGFRα mutant kinase profiling was performed with recombinant enzymes including wild-type KIT, KIT V560G, KIT V559D/T670I, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent