Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM25118'
TargetPlatelet-derived growth factor receptor beta(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25118BDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant PDGFRbeta (unknown origin) expressed in baculovirus infected insect cells using biotinylated peptide substrate GGLFDDPSYVNV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25118BDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  3.80nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2011
Entry Details
PCBioAssay
TargetPlatelet-derived growth factor receptor beta(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25118BDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  3.80nMAssay Description:Binding constant for PDGFRB kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25118BDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  3.80nMAssay Description:Binding constant for PDGFRB kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25118BDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25118BDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of PDGFR-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25118BDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataEC50:  51nMAssay Description:Inhibition of PDGFRbeta phosphorylation expressed in human KM12L4A cells Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed