Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Poly(ADP-ribose) glycohydrolase' and Ligand = 'BDBM371100'
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM371100(US10239843, Example 207 | US10239843, Example 285)
Affinity DataIC50:  38nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM371100(US10239843, Example 207 | US10239843, Example 285)
Affinity DataIC50:  134nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM371100(US10239843, Example 207 | US10239843, Example 285)
Affinity DataEC50:  120nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM371100(US10239843, Example 207 | US10239843, Example 285)
Affinity DataEC50:  38nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed