Found 2 Enz. Inhib. hit(s) with Target = 'Poly(ADP-ribose) glycohydrolase' and Ligand = 'BDBM50508413'
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair