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Found 3 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM209856'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical

US Patent
LigandPNGBDBM209856(US9273052, 15 | US9566277, 15)
Affinity DataIC50:  2.30nMT: 2°CAssay Description:The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical

US Patent
LigandPNGBDBM209856(US9273052, 15 | US9566277, 15)
Affinity DataIC50:  2.30nMT: 2°CAssay Description:he assay described below is to determine the activity of the compounds of the present invention for inhibiting the enzyme activity of PARP by using t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical

US Patent
LigandPNGBDBM209856(US9273052, 15 | US9566277, 15)
Affinity DataEC50:  51nMAssay Description:Inhibition of PARP in human HeLa cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed