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Found 3 Enz. Inhib. hit(s) with Target = 'Polycomb protein EED' and Ligand = 'BDBM50235644'
TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235644(CHEMBL4065766)
Affinity DataKi:  0.740nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235644(CHEMBL4065766)
Affinity DataIC50:  100nMAssay Description:Inhibition of EED in human OCILY19 cells assessed as reduction in H3K27 trymethylation measured after 6 days by alphaLISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235644(CHEMBL4065766)
Affinity DataIC50:  190nMAssay Description:Inhibition of EED in human G401 cells assessed as reduction in H3K27 trymethylation measured after 6 days by alphaLISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed