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Found 3 Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 2' and Ligand = 'BDBM60579'
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM60579((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...)
Affinity DataKi:  374nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 1.25 uM by Line-Weaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM60579((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...)
Affinity DataKi:  840nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 20 uM by Line-Weaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM60579((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed