Found 2 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50142750' TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 255nMAssay Description:Inhibition of 5-LOX in human intact polymorphonuclear leukocytes preincubated for 15 mins with CaCl2, A23187 measured after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as LTB4 formation preincubated ...More data for this Ligand-Target Pair
