Found 8 Enz. Inhib. hit(s) with Target = 'Potassium-transporting ATPase alpha chain 1/subunit beta' and Ligand = 'BDBM50241343' TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Ortho Pharmaceutical
Curated by ChEMBL
Ortho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Ortho Pharmaceutical
Curated by ChEMBL
Ortho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Ortho Pharmaceutical
Curated by ChEMBL
Ortho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of [14C]-aminopyrine (AP) accumulation stimulated by dibutyryl cyclic AMP in isolated rabbit parietal cellsMore data for this Ligand-Target Pair
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Ortho Pharmaceutical
Curated by ChEMBL
Ortho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibitory activity against H+/K+ ATPase prepared from canine fundic mucosaMore data for this Ligand-Target Pair
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:In vitro inhibition against H+/K+ ATPase from porcine gastric mucosal membrane vesiclesMore data for this Ligand-Target Pair
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Ortho Pharmaceutical
Curated by ChEMBL
Ortho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMpH: 7.4Assay Description:Inhibition of H+/K+ ATPase activity in buffered solution (pH 7.4)More data for this Ligand-Target Pair
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Ortho Pharmaceutical
Curated by ChEMBL
Ortho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.24E+4nMAssay Description:Compound was tested in vitro for H+/K+ ATPase activity in rabbit stomach preparationsMore data for this Ligand-Target Pair
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Sus scrofa (Pig))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Activity was evaluated by measuring the inhibition of isolated hog H+/K+ ATPaseMore data for this Ligand-Target Pair
