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Found 9 Enz. Inhib. hit(s) with Target = 'Probable G-protein coupled receptor 88' and Ligand = 'BDBM50554975'
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))TBA
LigandPNGBDBM50554975(CHEMBL4595209)
Affinity DataKi:  224nMAssay Description:Displacement of [3H]RTI-33 from GPR88 (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))TBA
LigandPNGBDBM50554975(CHEMBL4595209)
Affinity DataEC50:  47nMAssay Description:Agonist activity at GPR88 (unknown origin) expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Mus musculus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50554975(CHEMBL4595209)
Affinity DataEC50:  25nMAssay Description:Agonist activity at GPR88 in mouse striatal membrane assessed as [35S]-GTPgammaS-binding by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))TBA
LigandPNGBDBM50554975(CHEMBL4595209)
Affinity DataKd:  85nMAssay Description:Binding affinity to PPLS-HA tagged human GPR88 expressed in CHO cell membrane by filtration methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))TBA
LigandPNGBDBM50554975(CHEMBL4595209)
Affinity DataEC50:  45nMAssay Description:Agonist activity at GPR88 (unknown origin) expressed in CHO cells coexpressing PPLS-HA assessed as reduction in forskolin-stimulated cAMP production ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProbable G-protein coupled receptor 88(Mus musculus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50554975(CHEMBL4595209)
Affinity DataKd:  41nMAssay Description:Binding affinity to GPR88 in mouse striatal membrane by filtration methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))TBA
LigandPNGBDBM50554975(CHEMBL4595209)
Affinity DataEC50:  45nMAssay Description:Agonist activity at GPR88 (unknown origin) expressed in CHO cells coexpressing PPLS-HA assessed as reduction in forskolin-stimulated cAMP production ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))TBA
LigandPNGBDBM50554975(CHEMBL4595209)
Affinity DataEC50:  47nMAssay Description:Agonist activity at GPR88 (unknown origin) expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 88(Homo sapiens (Human))TBA
LigandPNGBDBM50554975(CHEMBL4595209)
Affinity DataEC50:  45nMAssay Description:Agonist activity at GPR88 (unknown origin) transfected in HEK293 cells assessed as cAMP level by GloSensor cAMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed