Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50219259'
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219259(5-(3-Cyclobutyl-2-oxo-2,3-dihydro-1H-benzoimidazol...)
Affinity DataIC50:  10.9nMAssay Description:Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219259(5-(3-Cyclobutyl-2-oxo-2,3-dihydro-1H-benzoimidazol...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at progesterone receptor expressed in T47D cells assesed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219259(5-(3-Cyclobutyl-2-oxo-2,3-dihydro-1H-benzoimidazol...)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed