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Found 4 Enz. Inhib. hit(s) with Target = 'Prokineticin receptor 1' and Ligand = 'BDBM121205'
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121205(US8722896, (+)-(2S)-2-Methyl-3-(indol-7- ylmethyla...)
Affinity DataKi:  4.90nM ΔG°:  -49.3kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121205(US8722896, (+)-(2S)-2-Methyl-3-(indol-7- ylmethyla...)
Affinity DataKi:  6.96nM ΔG°:  -48.4kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121205(US8722896, (+)-(2S)-2-Methyl-3-(indol-7- ylmethyla...)
Affinity DataKi:  8.12nM ΔG°:  -48.0kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProkineticin receptor 1(Cricetulus griseus (Chinese hamster))
The Regents of The University of California

US Patent
LigandPNGBDBM121205(US8722896, (+)-(2S)-2-Methyl-3-(indol-7- ylmethyla...)
Affinity DataKi:  67.4nM ΔG°:  -42.6kJ/moleT: 2°CAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
In DepthDetails US Patent