Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase FAP' and Ligand = 'BDBM50200723'
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
Affinity DataKi:  7.5nMAssay Description:Inhibitiory constant against FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
Affinity DataIC50:  93nMAssay Description:Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human recombinant FAP expressed in Hi5 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed