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Found 4 Enz. Inhib. hit(s) with Target = 'Proprotein convertase subtilisin/kexin type 9' and Ligand = 'BDBM50609098'
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))TBA
LigandPNGBDBM50609098(CHEMBL5278470)
Affinity DataIC50:  40nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by ab20 addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))TBA
LigandPNGBDBM50609098(CHEMBL5278470)
Affinity DataIC50:  720nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by EGF(A) addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))TBA
LigandPNGBDBM50609098(CHEMBL5278470)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of human PCSK9 preincubated for 30 mins followed by LDLR addition and measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))TBA
LigandPNGBDBM50609098(CHEMBL5278470)
Affinity DataKd:  390nMAssay Description:Binding affinity to human PCSK9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed