Found 21 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM35847'
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Binding affinity at human prostaglandin EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]PGE4 from human EP4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Kyoto University
Curated by PDSP Ki Database
Kyoto University
Curated by PDSP Ki Database
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Kyoto University
Curated by PDSP Ki Database
Kyoto University
Curated by PDSP Ki Database
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Kyoto University
Curated by PDSP Ki Database
Kyoto University
Curated by PDSP Ki Database
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Binding affinity to EP4 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibitory activity against human EP4 receptor expressed in HEK293 ebna cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]prostaglandin E2 from recombinant human full length EP4 receptor expressed in Chem-1 cell membranes after 60 mins by liquid scint...More data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0200nMAssay Description:Agonist activity at human EP4 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
Affinity DataEC50: 7.5nMAssay Description:Agonist activity at human EP4 receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 mins by HTRF methodMore data for this Ligand-Target Pair
Affinity DataEC50: 0.583nMAssay Description:Agonist activity at human EP4 receptor expressed in HEK293T/17 cells assessed as increase in intracellular cAMP level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Agonist activity against rat EP4 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Agonist activity at human EP4 receptor by cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.5nMAssay Description:Agonist activity at rat EP4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Binding affinity towards EP1 receptor expressed in HEK293 ebna cells recombinantly expressing the corresponding human prostanoid cDNAsMore data for this Ligand-Target Pair