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Found 6 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM50097346'
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM50097346((+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid ...)
Affinity DataKi:  87nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Zafes/Liff/Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50097346((+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid ...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of ovine COX1 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM50097346((+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid ...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibitory activity against cell-free canine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Zafes/Liff/Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50097346((+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid ...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of ovine COX-1 assessed as residual activity by measuring formation of 12-HHT from arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Zafes/Liff/Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50097346((+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid ...)
Affinity DataIC50:  2.23E+4nMAssay Description:Inhibition of ovine COX1 pre-incubated for 10 mins before arachidonic acid substrate addition by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM50097346((+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid ...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed