Found 21 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50056999' TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 15nMAssay Description:Inhibitory activity of the compound was evaluated against human Prostaglandin G/H synthase 2 was determinedMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 23nMAssay Description:Inhibition of purified COX2 assessed as formation of oxidized TMPD during reduction og PGG2 to PGH2 preincubated for 15 mins by chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of ovine COX2 assessed as PGF2alpha level by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 600nMAssay Description:In vitro inhibition activity against cyclooxygenase 2 with the compound dissolved in DMSOMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 700nMAssay Description:Inhibition of COX-2 in human whole blood assessed as PGE2 level in plasma after 5 mins by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 in LPS-stimulated human whole blood assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 1.30E+3nMAssay Description:The inhibitory activity against cyclooxygenase Prostaglandin G/H synthase 2 (COX-2) measured as PGE-2 production after blood coagulation using human ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate incubated for 5 to 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate measured after 10 mins by fluorometric based multimode microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of COX2 in LPS-stimulated human whole blood assessed as TXB2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-induced PGE2 production after 24 hrs by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 at 10 ug/mL expressed as the mean percent inhibition of control PGE-2 productionMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of human COX2 expressed in baculovirus infected sf21 cells assessed as reduction in formation of oxidized TMPD using arachidonic acid as s...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 2.31E+5nMAssay Description:Inhibition of human recombinant COX2 expressed in baculovirus infected SF21 cellMore data for this Ligand-Target Pair
