Found 13 Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-1' and Ligand = 'BDBM50069989' TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of PGPH activity of human 26S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Evaluated for norepinephrine as agonist.More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human HL60 cells using Z-nLPnLDaminoluciferin as substrate pretreated for 2 hrs followed by sub...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of caspase-like activity of 20S proteasome in human HL60 cells using Z-nLPnLDaminoluciferin as substrate after 2 hrs by fluorescence analy...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Reversible inhibition of human erythrocyte derived 20S proteasome subunit beta1 after 30 mins by fluorogenic assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of 20S proteasome beta 1c (unknown origin) after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human 20S constitutive proteasome beta 1 subunit caspase-like activity using fluorogenic peptide Ac-nLPnLD-AMC as substrate in presence...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of caspase-like activity of human 20S proteasomeMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 104nMAssay Description:Inhibition of human hepatic cell derived 20s constitutive proteasome beta1 caspase-like activity using Suc-LLE-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 104nMAssay Description:Inhibition of human hepatic cell derived 20s constitutive proteasome beta1 caspase-like activity using Suc-LLE-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of caspase-like activity of human 20S proteasome beta 1 subunit using Ac-nLPnLD-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 297nMAssay Description:Inhibition of 20S proteasome beta1 subunit (unknown origin) using Z-LLE-AMC as flurogenic substrate measured after 1 hr by fluorescence based analysi...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Nagahama Institute Of Bio-Science And Technology
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of PGPH activity of human 20S proteasome using Z-LLE-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
