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Found 15 Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-8' and Ligand = 'BDBM50099663'
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  25nMAssay Description:Inhibition of proteasome subunit beta-5i in human RPMI8226 cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  39nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  39nMAssay Description:Inhibition of LMP7 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  573nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  573nMAssay Description:Inhibition of LMP7 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of immunoproteasome subunit LMP7 in human DOX40 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of immunoproteasome subunit LMP7 in human INA60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of immunoproteasome subunit LMP7 in human MM.1R cells assessed as reduction in cell viability incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of immunoproteasome subunit LMP7 in human KMS12PE cells assessed as reduction in cell viability incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of immunoproteasome subunit LMP7 in human RPMI8226 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of immunoproteasome subunit LMP7 in human MM.1S cells assessed as reduction in cell viability incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of immunoproteasome subunit LMP7 in human OPM1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of immunoproteasome subunit LMP7 in human LR5 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099663(CHEMBL3319482)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of immunoproteasome subunit OPM2 in human OPM1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed