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Found 3 Enz. Inhib. hit(s) with Target = 'Protein O-GlcNAcase' and Ligand = 'BDBM141965'
TargetProtein O-GlcNAcase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM141965(US8927507, 16)
Affinity DataKi:  2.80nM ΔG°:  -48.8kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM141965(US8927507, 16)
Affinity DataKi:  2.80nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein O-GlcNAcase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM141965(US8927507, 16)
Affinity DataEC50:  152nMAssay Description:Inhibition of OGA in rat PC12 cells assessed as OGlcNAcylated protein level incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed