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Found 2 Enz. Inhib. hit(s) with Target = 'Protein O-GlcNAcase' and Ligand = 'BDBM240644'
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics

US Patent
LigandPNGBDBM240644(US9409924, (3aR,5R,6R,7S,7aR)-2-(ethylamino)-7-flu...)
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics

US Patent
LigandPNGBDBM240644(US9409924, (3aR,5R,6R,7S,7aR)-2-(ethylamino)-7-flu...)
Affinity DataEC50:  13nMAssay Description:Inhibition of O-GlcNAcase, which removes O-GlcNAc from cellular proteins, results in an increase in the level of O-GlcNAcylated protein in cells. An ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent