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Found 3 Enz. Inhib. hit(s) with Target = 'Protein translocase subunit SecA 1' and Ligand = 'BDBM50498946'
TargetProtein translocase subunit SecA 1(Staphylococcus aureus (strain NCTC 8325))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50498946(CHEMBL3735815)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposomal ion channel activity in Xenopus laevis oocytes incubated for 3 hrs measured by recordi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein translocase subunit SecA 1(Staphylococcus aureus (strain NCTC 8325))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50498946(CHEMBL3735815)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposome dependent proOmpA translocation incubated for 1.5 hrs measured by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein translocase subunit SecA 1(Staphylococcus aureus (strain NCTC 8325))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50498946(CHEMBL3735815)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Staphylococcus aureus ATCC 35556 SecA1 expressed in Escherichia coli BL21-gammaDE3 assessed as reduction in intrinsic ATPase activity i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed