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Found 5 Enz. Inhib. hit(s) with Target = 'Protein-S-isoprenylcysteine O-methyltransferase' and Ligand = 'BDBM50327696'
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327696(2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetamide | CHE...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327696(2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetamide | CHE...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant Icmt (unknown origin) expressed in Sf9 cells assessed as transfer of methyl group from [3H]-S-adenosylmethionine to [3H]-bi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327696(2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetamide | CHE...)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibition of ICMT expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327696(2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetamide | CHE...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant ICMT (unknown origin) expressed in sf9 cells using biotin S-farnesyl-L-cysteine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50327696(2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetamide | CHE...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H]-AdoMet after 20 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed