Found 8 Enz. Inhib. hit(s) with Target = 'Protein-tyrosine kinase 6' and Ligand = 'BDBM13216' TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of BRK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of BRK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of BRK pretreated for 30 mins by microplate readerMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataKd: 7.80nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataKd: 7.80nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataKd: 7.80nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
