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Found 4 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM16307'
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16307(2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...)
Affinity DataKi:  1.05E+4nM ΔG°:  -28.1kJ/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16307(2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...)
Affinity DataKi:  1.05E+4nMAssay Description:Binding affinity to thrombin in presence of Zn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16307(2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...)
Affinity DataKi: >1.50E+5nMAssay Description:Binding affinity to thrombin in absence of Zn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Arris

LigandPNGBDBM16307(2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...)
Affinity DataKi: >1.00E+6nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed