Found 3 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase ROS' and Ligand = 'BDBM374727'
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Yantai University
Curated by ChEMBL
Yantai University
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of human ROS1 using KKKSPGEYVNIEFG as substrate in presence of ATP by radiometric HotSpot kinase assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Yantai University
Curated by ChEMBL
Yantai University
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 120 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Yantai University
Curated by ChEMBL
Yantai University
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibition of ROS1 G2032R mutant (unknown origin)More data for this Ligand-Target Pair