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Report error Found 9 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM161376'
TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataKd:  10nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataKd:  10nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Respivert

US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataKd:  10nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Respivert

US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataKd:  10nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Respivert

US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataIC50: 22nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Respivert

US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataIC50: 22nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Respivert

US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataIC50: 22nMAssay Description:c-Src and SyK: The enzyme inhibitory activities of compounds disclosed herein were determined by FRET using synthetic peptides labelled with both don...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Respivert

US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataIC50: 22nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Respivert

US Patent
LigandPNGBDBM161376(US9108950, 1 | US9724347, Example 1 | US10238658, ...)
Affinity DataIC50: 22nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashio...More data for this Ligand-Target Pair
In DepthDetails
US Patent