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Found 3 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret [V804L]' and Ligand = 'BDBM311622'
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804L](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM311622(Ex. Cpd. 59 | US10807986, Example 59 | US11046696,...)
Affinity DataIC50:  0.300nMAssay Description:Regarding the conditions for measurement of in vitro inhibitory activity of compounds against RET (V804L) (i.e., RET with V804L mutation) kinase acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804L](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM311622(Ex. Cpd. 59 | US10807986, Example 59 | US11046696,...)
Affinity DataIC50:  0.300nMAssay Description:Regarding the conditions for measurement of in vitro inhibitory activity of compounds against RET (V804L or V804M) (i.e., RET with V804L or V804M mut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804L](Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM311622(Ex. Cpd. 59 | US10807986, Example 59 | US11046696,...)
Affinity DataIC50:  0.800nMAssay Description:Regarding the conditions for measurement of in vitro inhibitory activity of compounds against RET kinase activity, the website of AnaSpec states that...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent