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Found 3 Enz. Inhib. hit(s) with Target = 'Receptor protein serine/threonine kinase' and Ligand = 'BDBM50262685'
TargetReceptor protein serine/threonine kinase(Danio rerio (Zebrafish))
Vanderbilt University

LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataEC50:  2.50E+3nMAssay Description:The effects on zebrafish embryos with respect to the dorsoventral (DV) axis. For dorsalization, the EC100 (effective concentration 100%) represents t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor protein serine/threonine kinase(Danio rerio (Zebrafish))
Vanderbilt University

LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataEC50:  2.00E+4nMAssay Description:For nonspecific toxicity, the EC100 represents the concentration when 100% of the treated embryos exhibit either early lethality within hours of comp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor protein serine/threonine kinase(Danio rerio (Zebrafish))
Vanderbilt University

LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataEC50:  5.00E+3nMAssay Description:For ISV disruption, the EC50 represents the concentration when the formation of about 50% of the ISVs is inhibited.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed