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Found 2 Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM50466038'
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Sichuan University/Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Sichuan University/Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataKd:  4.40nMAssay Description:Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed