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Found 1 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM112497'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM112497(US8623885, 18b)
Affinity DataIC50:  2.30nMpH: 7.6Assay Description:The FLT3 inhibitory activity of the CDK4/6-FLT3 inhibitors was determined with a HTRF kinase assay. The FLT3 enzyme (GST-FLT3 fusion) was purchased f...More data for this Ligand-Target Pair
In DepthDetails US Patent