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Found 3 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50453202'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50453202(CHEMBL4207317)
Affinity DataIC50:  1nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant human FLT3 (R571 to S993 residues) ITD mutant expressed in Sf9 insect cells using poly (Ala,Glu,L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50453202(CHEMBL4207317)
Affinity DataIC50:  3nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant human FLT3 (R571 to S993 residues) D835Y mutant expressed in Sf9 insect cells using poly (Ala,Glu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50453202(CHEMBL4207317)
Affinity DataIC50:  13nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant wild type human FLT3 (R571 to S993 residues) expressed in Sf9 insect cells using poly (Ala,Glu,Ly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed