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Found 5 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50568687'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of South Australia

Curated by ChEMBL
LigandPNGBDBM50568687(CHEMBL4876697)
Affinity DataKi:  2nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of South Australia

Curated by ChEMBL
LigandPNGBDBM50568687(CHEMBL4876697)
Affinity DataKi:  9nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using Glu/Tyr peptide substrate incubated for 120 mins measured after 40 mins incubation under dark by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of South Australia

Curated by ChEMBL
LigandPNGBDBM50568687(CHEMBL4876697)
Affinity DataKi:  47nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) incubated for 120 mins by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of South Australia

Curated by ChEMBL
LigandPNGBDBM50568687(CHEMBL4876697)
Affinity DataKi:  54nMAssay Description:Inhibition of FLT3 F594_R595insR mutant (unknown origin) incubated for 120 mins by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of South Australia

Curated by ChEMBL
LigandPNGBDBM50568687(CHEMBL4876697)
Affinity DataKi:  64nMAssay Description:Inhibition of FLT3 R595_E596insEY mutant (unknown origin) incubated for 120 mins by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed