Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50593961'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50593961(CHEMBL5195819)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50593961(CHEMBL5195819)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of human recombinant His-tagged FLT3 kinase domain (564 to 958 residues) expressed in baculovirus expression system incubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50593961(CHEMBL5195819)
Affinity DataKd:  0.0154nMAssay Description:Binding affinity to FLT3 ITD/F691L double mutant (unknown origin) by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed