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Found 3 Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM29934'
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

LigandPNGBDBM29934(piperidine-1-carboxamide, 7h)
Affinity DataIC50:  40nMpH: 7.0 T: 2°CAssay Description:The activity of renin inhibitors in vitro was measured using the FRET assay, which was carried out in flat-bottom white opaque microtiter plates. The...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

LigandPNGBDBM29934(piperidine-1-carboxamide, 7h)
Affinity DataIC50:  40nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

LigandPNGBDBM29934(piperidine-1-carboxamide, 7h)
Affinity DataIC50:  447nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed