Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM479494'
TargetReplicase polyprotein 1ab(2019-nCoV)
Cleveland Clinic

LigandPNGBDBM479494(ML300-based SC inhibitor 33 | US20240239772, Compo...)
Affinity DataIC50: 312nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cleveland Clinic

LigandPNGBDBM479494(ML300-based SC inhibitor 33 | US20240239772, Compo...)
Affinity DataIC50: 312nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
Cleveland Clinic

LigandPNGBDBM479494(ML300-based SC inhibitor 33 | US20240239772, Compo...)
Affinity DataIC50: 418nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Cleveland Clinic

LigandPNGBDBM479494(ML300-based SC inhibitor 33 | US20240239772, Compo...)
Affinity DataIC50: 418nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent