Found 8 Enz. Inhib. hit(s) with Target = 'Retinal dehydrogenase 2' and Ligand = 'BDBM50466622' TargetRetinal dehydrogenase 2(Gallus gallus)
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant chick RALDH2 expressed in Escherichia coli BL21(DE3) cells using RAL as substrate measured after 30 ...More data for this Ligand-Target Pair
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 64nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human RALDH2 using RAL as substrate measured after 30 mins in presence of NADH by Morrison's plot an...More data for this Ligand-Target Pair
TargetRetinal dehydrogenase 2(Gallus gallus)
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 128nMAssay Description:Inhibition of N-terminal His6-tagged recombinant chick RALDH2 expressed in Escherichia coli BL21(DE3) cells up to 500 nM using RAL as substrate prein...More data for this Ligand-Target Pair
TargetRetinal dehydrogenase 2(Gallus gallus)
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of RALDH2 in choroidal cytosol fraction from 4 day recovering chick assessed as inhibition of ATRA synthesis pre-incubated for 20 mins fol...More data for this Ligand-Target Pair
TargetRetinal dehydrogenase 2(Gallus gallus)
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of N-terminal His6-tagged recombinant chick RALDH2 expressed in Escherichia coli BL21(DE3) cells using RAL as substrate preincubated for 2...More data for this Ligand-Target Pair
TargetRetinal dehydrogenase 2(Gallus gallus)
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
Affinity DataIC50: 187nMAssay Description:Inhibition of chick RALDH2 expressed in doxycycline-inducible HEK293 cells assessed as inhibition of ATRA synthesis after 24 hrs in presence of ATRA ...More data for this Ligand-Target Pair
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
Affinity DataIC50: 191nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human RALDH2 using RAL as substrate preincubated for 20 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
TargetRetinal dehydrogenase 2(Gallus gallus)
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
University Of Oklahoma Health Sciences Center
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Inhibition of RALDH2 in living intact choroid isolated from 4 day recovering chick eyes assessed as inhibition of ATRA synthesis after 24 hrs in pres...More data for this Ligand-Target Pair
