Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor alpha' and Ligand = 'BDBM50032219'
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
CIRD GALDERMA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataKi:  21nMAssay Description:Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
CIRD GALDERMA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataIC50:  36nMAssay Description:Binding affinity against retinoic Acid alpha receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
CIRD GALDERMA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataEC50:  21nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
CIRD GALDERMA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataEC50:  85nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
CIRD GALDERMA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataEC50:  21nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
CIRD GALDERMA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at human RARalpha expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
CIRD GALDERMA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataEC50:  30nMAssay Description:Agonist activity for retinoic acid receptor RAR alpha in transcriptional activation assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
CIRD GALDERMA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataEC50:  21nMAssay Description:Transcriptional activation of retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
CIRD GALDERMA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataEC50:  30nMAssay Description:Transactivation potency of the compound was determined for Retinoic acid receptor alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
CIRD GALDERMA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataKd:  36nMAssay Description:Binding affinity for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
CIRD GALDERMA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataEC50:  30nMAssay Description:Binding affinity against retinoic Acid alpha receptors cotransfected into CV-1 cellsMore data for this Ligand-Target Pair