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Found 4 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM528673'
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataIC50:  1.02E+3nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataIC50:  1.28E+3nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataKd:  89nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Bioaxone Biosciences

US Patent
LigandPNGBDBM528673(US11198680, Compound Racemic-BA-1049-Lot-2)
Affinity DataKd:  54nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent