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Found 1 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM25384'
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University of Pennsylvania

LigandPNGBDBM25384(7-benzyl-8-(3,5-dimethyl-1H-pyrazol-1-yl)-1,3-dime...)
Affinity DataIC50:  5.77E+4nMpH: 7.0 T: 2°CAssay Description:BRAF kinase activity was quantified using an ELISA-based MEK phosphorylation assay. IC50 values were derived from the sigmoidal dose-response curve f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed