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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50176320'
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50176320(CHEMBL381447 | N-(2-(4-(4-chloro-3-hydroxyphenyl)-...)
Affinity DataIC50:  14nMAssay Description:Inhibition bRaf kinase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50176320(CHEMBL381447 | N-(2-(4-(4-chloro-3-hydroxyphenyl)-...)
Affinity DataKd:  10nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed