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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf [416-766,V600E]' and Ligand = 'BDBM322528'
TargetSerine/threonine-protein kinase B-raf [416-766,V600E](Homo sapiens (Human))
Redx Pharma

US Patent
LigandPNGBDBM322528(5-[3-[4-(3-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...)
Affinity DataIC50:  1nMAssay Description:To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [416-766,V600E](Homo sapiens (Human))
Redx Pharma

US Patent
LigandPNGBDBM322528(5-[3-[4-(3-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...)
Affinity DataIC50: <4nMAssay Description:To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent