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Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf [V600E]' and Ligand = 'BDBM317685'
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317685(US11337976, Compound P-0056 | US20230277534, Compo...)
Affinity DataIC50: <100nMAssay Description:Assays for biochemical and cell based activity are known in the art, for example, as described in PCT publication WO 2007/002433, the disclosure of w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317685(US11337976, Compound P-0056 | US20230277534, Compo...)
Affinity DataIC50: <100nMAssay Description:The biochemical activity IC50 values are determined with respect to inhibition of B-Raf V600E kinase activity or p-Erk kinase activity, where inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317685(US11337976, Compound P-0056 | US20230277534, Compo...)
Affinity DataIC50: <100nMAssay Description:For example, the biochemical activity IC50 values are determined with respect to inhibition of B-Raf V600E kinase activity or p-Erk kinase activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent