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Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50332136'
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332136((S)-2-phenyl-4-(piperidin-3-ylamino)thieno[3,2-c]p...)
Affinity DataIC50:  4nMAssay Description:Inhibition of His-tagged CHK1 after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332136((S)-2-phenyl-4-(piperidin-3-ylamino)thieno[3,2-c]p...)
Affinity DataIC50:  7nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332136((S)-2-phenyl-4-(piperidin-3-ylamino)thieno[3,2-c]p...)
Affinity DataEC50:  26nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed