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Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk2' and Ligand = 'BDBM4814'
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  17nMAssay Description:Inhibition of CHK2 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd:  7.10nMAssay Description:Binding affinity to CHEK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd:  10nMAssay Description:Binding constant for CHEK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed