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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM50435736'
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50435736(CHEMBL2392552 | US9266890, I-3)
Affinity DataIC50:  12nMAssay Description:Inhibition of PLK1 (unknown origin) using biotin-AGAGTVPESIHSFIGDGLV as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50435736(CHEMBL2392552 | US9266890, I-3)
Affinity DataKd:  0.570nMAssay Description:In vitro Plk1 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
In DepthDetails US Patent